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Have a medium size carry on . I have found this is the perfect size, it fits in all over head compartments, fits under the seat, and is easy to roll around a city if you make a side trip.
Use these awesome pack-it envelopes . If you fold the items correctly you can fit up to 7-12 items in this envelope. Hubby I can only fit 7, but for the teeanger and I can fit up to 12!
Use these awesome pack it cubes. These are great for keeping socks and undies together, or shirts/shorts that you can roll. I was able to fit a week's worth of undies and socks into one cube for the teenager and I.
Don't over pack. For a week long trip you don't need a ton of stuff, we went for two weeks and I packed enough for one week and just washed items since I was staying with a friend. Things like jeans, shorts, or skirts can be worn multiple times before needing to be washed, so bringing just a couple items to fit different situations will work.
Utilize your personal item. I typically put individual toiletries in our personal item. For example, my purse will carry any feminine hygene products and/or make-up I need.
Fold your dirty laundry. This may sound bizarre but when you are at the end of your trip and won't be needing to keep dirty and clean laundry separate just fold up the laundry as it will help you fit it all back in.
Do you have an great suitcase organization tips we should know about?